What Is Semax?
Semax is a synthetic heptapeptide based on the ACTH(4-7) fragment (Met-Glu-His-Phe) of adrenocorticotropic hormone, extended with the Pro-Gly-Pro (PGP) tripeptide sequence to enhance metabolic stability and blood-brain barrier penetration. The resulting compound — ACTH(4-7)PGP — is more resistant to enzymatic degradation than the parent ACTH fragment.
Preclinical research has investigated Semax primarily in neurological models: neuroprotection following ischaemic events, BDNF and NGF upregulation, serotonin and dopamine pathway modulation, and cognitive performance. It is frequently compared with Selank — another Soviet-derived neuropeptide with anxiolytic research applications — as part of the broader neuropeptide research literature.
For anxiolytic neuropeptide research, see the Selank page. For research use only.
Semax Products
Two concentrations available, supplied in boxes of 10 research-grade vials.
Why Researchers Choose Eternal Peptides
Janoshik-Verified Every Batch
HPLC purity, mass spectrometry identity, sterility (USP), endotoxin (LAL), and heavy metals (ICP-MS). COA independently verifiable at janoshik.com.
Australian-Owned, ABN Registered
ABN-registered Australian business dispatching domestically. ABN shown on all invoices.
Wholesale Box Pricing
Supplied in boxes of 10 vials at wholesale pricing. Structured for research procurement budgets.
1-2 Day Dispatch
Orders dispatched within 1-2 business days from Australia. COA included with every order.
Frequently Asked Questions
Where can I buy Semax in Australia? +
Eternal Peptides Wholesale is an Australian-owned, ABN-registered distributor supplying Semax for research purposes. SX05 (5mg, box of 10) is $396.00 and SX10 (10mg, box of 10) is $594.00. Janoshik-verified with COAs on each product page. Dispatched within 1-2 business days. For research use only.
What is Semax used for in research? +
Semax is studied in neuroprotection (particularly ischaemic models), BDNF and NGF upregulation, serotonin and dopamine pathway effects, anxiety models, and cognitive function research. Its ACTH(4-7) core is linked to memory and learning pathways in the preclinical literature. For research use only.
What is the difference between SX05 and SX10? +
SX05 is 5mg per vial (box of 10, $396.00). SX10 is 10mg per vial (box of 10, $594.00). Concentration selection depends on your research protocol. Both are Janoshik-verified. For research use only.
How does Semax differ from Selank? +
Semax (ACTH(4-7)PGP) is primarily studied for neuroprotective and cognitive effects via BDNF upregulation and monoamine pathway modulation. Selank (tuftsin analogue) is primarily studied in anxiety and stress-response models via GABAergic and serotonergic pathways. The two compounds are often compared in neuropeptide research. See the Selank page. For research use only.
How is Semax quality verified? +
Every batch is tested by Janoshik Analytical — HPLC purity, mass spectrometry identity, sterility (USP), endotoxin (LAL), heavy metals (ICP-MS). COA published on product page, independently verifiable at janoshik.com. For research use only.
How quickly is Semax dispatched? +
Orders are dispatched within 1-2 business days of payment confirmation from Australia. COA documentation is included with every order.